Our Research

Mechano-regulation of inflammatory signals in embryonic aorta for blood development 

Exploring adipose immune cells’ response to cold exposure at a cellular level 

Identifying enhancer regions that can regulate gene expression in reactive astrogliosis, offering potential therapeutic targets for the treatment or prevention of Alzheimer’s disease.

Understanding the attitudes of patients and health professionals regarding the use of using spatial sequencing technology for diagnosing Non-Small Cell Lung Cancer (NSCLC). 
 

Development of pre-clinical platforms for enhancing antibody quality in vaccine design

Genetically guided therapy choice for gastrointestinal autoimmune disorders

A Tonsillar Organoid System to Study Human Diseases

Sharing data for the benefit of the biomedical community

Finding a common cause of autoimmune disease

CRISPRi screening of regulatory regions using snRNA-seq readout and integration with Hi-C data.

Single-cell analyses of interacting cells in circulating tumour cell clusters.

Dissecting the immunopathogenesis of coeliac disease by identifying cells going rogue

Defining the molecular basis of effective antigen cross-presentation via integrated single cell imaging and sequencing

Predicting Time to Environment-Dependent Emergence of Myeloma in Patients (PreEEMPT)

Synthetic reference controls for single-cell sequencing

Role of genetic variation contributing to Covid-19 severity of response – understanding host genetics and immune function

Single-cell sequencing analysis. Fast and scalable denoising, imputation and integration of single cell multi-omics with signal processing based analyses.

Detecting single cell somatic mutations from long-read techniques

Single-cell sequencing analysis. Fast and scalable denoising, imputation and integration of single cell multi-omics with signal processing based analyses.