Molecular basis of antigen cross-presentation

Defining the molecular basis of effective antigen cross-presentation via integrated single cell imaging and sequencing

The societal benefit of the project is the implementation of interdisciplinary methods to profile the molecular basis of complex behaviour in immune cells. As T cell-based immunotherapies as well as DC vaccines become a reality in treatment of cancer and infection, the ability to screen for immune cells that are best performers at a complex task represents a key step in integrating machine learning, molecular data science, immunology, and therapeutic medicine towards a better standard of medical care. This research also brings together engineering, physics, and computer science expertise in order to develop innovative biomedical technologies. 

Chief Investigators

Co-Investigator Team