PUBLICATIONS
Journal articles
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Gunter HM; Youlten SE; Reis ALM; McCubbin T; Madala BS; Wong T; Stevanovski I; Cipponi A; Deveson IW; Santini NS; Kummerfeld S; Croucher PI; Marcellin E; Mercer TR, 2024, 'A universal molecular control for DNA, mRNA and protein expression', Nature Communications, 15, http://dx.doi.org/10.1038/s41467-024-46456-9
2024
Mattick JS; Amaral PP; Carninci P; Carpenter S; Chang HY; Chen LL; Chen R; Dean C; Dinger ME; Fitzgerald KA; Gingeras TR; Guttman M; Hirose T; Huarte M; Johnson R; Kanduri C; Kapranov P; Lawrence JB; Lee JT; Mendell JT; Mercer TR; Moore KJ; Nakagawa S; Rinn JL; Spector DL; Ulitsky I; Wan Y; Wilusz JE; Wu M, 2023, 'Long non-coding RNAs: definitions, functions, challenges and recommendations', Nature Reviews Molecular Cell Biology, 24, pp. 430 - 447, http://dx.doi.org/10.1038/s41580-022-00566-8
2023
Williams TC; Kroukamp H; Xu X; Wightman ELI; Llorente B; Borneman AR; Carpenter AC; Van Wyk N; Meier F; Collier TRV; Espinosa MI; Daniel EL; Walker RSK; Cai Y; Nevalainen HKM; Curach NC; Deveson IW; Mercer TR; Johnson DL; Mitchell LA; Bader JS; Stracquadanio G; Boeke JD; Goold HD; Pretorius IS; Paulsen IT, 2023, 'Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects', Cell Genomics, 3, http://dx.doi.org/10.1016/j.xgen.2023.100379
2023
Gunter HM; Idrisoglu S; Singh S; Han DJ; Ariens E; Peters JR; Wong T; Cheetham SW; Xu J; Rai SK; Feldman R; Herbert A; Marcellin E; Tropee R; Munro T; Mercer TR, 2023, 'mRNA vaccine quality analysis using RNA sequencing', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41354-y
2023
Mercer TR; Munro T; Mattick JS, 2022, 'The potential of long noncoding RNA therapies', Trends in Pharmacological Sciences, 43, pp. 269 - 280, http://dx.doi.org/10.1016/j.tips.2022.01.008
2022
Canson DM; Dumenil T; Parsons MT; O'Mara TA; Davidson AL; Okano S; Signal B; Mercer TR; Glubb DM; Spurdle AB, 2022, 'The splicing effect of variants at branchpoint elements in cancer genes', Genetics in Medicine, 24, pp. 398 - 409, http://dx.doi.org/10.1016/j.gim.2021.09.020
2022
Mercer T; Almond N; Crone MA; Chain PSG; Deshpande A; Eveleigh D; Freemont P; Fuchs S; Garlick R; Huggett J; Kammel M; Li PE; Milavec M; Marlowe EM; O’Sullivan DM; Page M; Pestano GA; Suliman S; Simen B; Sninsky JJ; Sopchak L; Tato CM; Vallone PM; Vandesompele J; White TJ; Zeichhardt H; Salit M, 2022, 'The Coronavirus Standards Working Group’s roadmap for improved population testing', Nature Biotechnology, 40, pp. 1563 - 1568, http://dx.doi.org/10.1038/s41587-022-01538-1
2022
Wei W; Zhao Q; Wang Z; Liau WS; Basic D; Ren H; Marshall PR; Zajaczkowski EL; Leighton LJ; Madugalle SU; Musgrove M; Periyakaruppiah A; Shi J; Zhang J; Mattick JS; Mercer TR; Spitale RC; Li X; Bredy TW, 2022, 'ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3', Cell Reports, 38, http://dx.doi.org/10.1016/j.celrep.2022.110546
2022
Anklam E; Bahl MI; Ball R; Beger RD; Cohen J; Fitzpatrick S; Girard P; Halamoda-Kenzaoui B; Hinton D; Hirose A; Hoeveler A; Honma M; Hugas M; Ishida S; Kass GEN; Kojima H; Krefting I; Liachenko S; Liu Y; Masters S; Marx U; McCarthy T; Mercer T; Patri A; Pelaez C; Pirmohamed M; Platz S; Ribeiro AJS; Rodricks JV; Rusyn I; Salek RM; Schoonjans R; Silva P; Svendsen CN; Sumner S; Sung K; Tagle D; Tong L; Tong W; Eijnden-van-Raaij JVD; Vary N; Wang T; Waterton J; Wang M; Wen H; Wishart D; Yuan Y; Slikker W, 2022, 'Emerging technologies and their impact on regulatory science', Experimental Biology and Medicine, 247, pp. 1 - 75, http://dx.doi.org/10.1177/15353702211052280
2022
Gong B; Deveson IW; Mercer T; Johann DJ; Jones W; Tong W; Xu J, 2022, 'Ultra-deep sequencing data from a liquid biopsy proficiency study demonstrating analytic validity', Scientific Data, 9, http://dx.doi.org/10.1038/s41597-022-01276-8
2022
Liu Z; Roberts R; Mercer TR; Xu J; Sedlazeck FJ; Tong W, 2022, 'Author Correction: Towards accurate and reliable resolution of structural variants for clinical diagnosis (Genome Biology, (2022), 23, 1, (68), 10.1186/s13059-022-02636-8)', Genome Biology, 23, http://dx.doi.org/10.1186/s13059-022-02773-0
2022
Ng SWK; Murphy T; King I; Zhang T; Mah M; Lu Z; Stickle N; Ibrahimova N; Arruda A; Mitchell A; Mai M; He R; Madala BS; Viswanatha DS; Dick JE; Chan S; Virtanen C; Minden MD; Mercer T; Stockley T; Wang JCY, 2022, 'A clinical laboratory–developed LSC17 stemness score assay for rapid risk assessment of patients with acute myeloid leukemia', Blood Advances, 6, pp. 1064 - 1073, http://dx.doi.org/10.1182/bloodadvances.2021005741
2022
Gunter HM; Youlten SE; Madala BS; Reis ALM; Stevanovski I; Wong T; Kummerfield SK; Deveson IW; Santini NS; Marcellin E; Mercer TR, 2022, 'Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing', Nature Communications, 13, pp. 6437, http://dx.doi.org/10.1038/s41467-022-34028-8
2022
Reis ALM; Deveson IW; Madala BS; Wong T; Barker C; Xu J; Lennon N; Tong W; Mercer TR, 2022, 'Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome', Genome Biology, 23, http://dx.doi.org/10.1186/s13059-021-02579-6
2022
Navone L; Moffitt K; Johnston WA; Mercer T; Cooper C; Spann K; Speight RE, 2022, 'Bioengineered textiles with peptide binders that capture SARS-CoV-2 viral particles', Communications Materials, 3, http://dx.doi.org/10.1038/s43246-022-00278-8
2022
Liu Z; Roberts R; Mercer TR; Xu J; Sedlazeck FJ; Tong W, 2022, 'Towards accurate and reliable resolution of structural variants for clinical diagnosis', Genome Biology, 23, http://dx.doi.org/10.1186/s13059-022-02636-8
2022
Mirzayi C; Renson A; Furlanello C; Sansone SA; Zohra F; Elsafoury S; Geistlinger L; Kasselman LJ; Eckenrode K; van de Wijgert J; Loughman A; Marques FZ; MacIntyre DA; Arumugam M; Azhar R; Beghini F; Bergstrom K; Bhatt A; Bisanz JE; Braun J; Bravo HC; Buck GA; Bushman F; Casero D; Clarke G; Collado MC; Cotter PD; Cryan JF; Demmer RT; Devkota S; Elinav E; Escobar JS; Fettweis J; Finn RD; Fodor AA; Forslund S; Franke A; Gilbert J; Grice E; Haibe-Kains B; Handley S; Herd P; Holmes S; Jacobs JP; Karstens L; Knight R; Knights D; Koren O; Kwon DS; Langille M; Lindsay B; McGovern D; McHardy AC; McWeeney S; Mueller NT; Nezi L; Olm M; Palm N; Pasolli E; Raes J; Redinbo MR; Rühlemann M; Balfour Sartor R; Schloss PD; Schriml L; Segal E; Shardell M; Sharpton T; Smirnova E; Sokol H; Sonnenburg JL; Srinivasan S; Thingholm LB; Turnbaugh PJ; Upadhyay V; Walls RL; Wilmes P; Yamada T; Zeller G; Zhang M; Zhao N; Zhao L; Bao W; Culhane A; Devanarayan V; Dopazo J; Fan X; Fischer M; Jones W; Kusko R; Mason CE; Mercer TR; Scherer A; Shi L; Thakkar S; Tong W; Wolfinger R; Hunter C, 2021, 'Reporting guidelines for human microbiome research: the STORMS checklist', Nature Medicine, 27, pp. 1885 - 1892, http://dx.doi.org/10.1038/s41591-021-01552-x
2021
Mercer TR; Xu J; Mason CE; Tong W, 2021, 'The Sequencing Quality Control 2 study: establishing community standards for sequencing in precision medicine', Genome Biology, 22, http://dx.doi.org/10.1186/s13059-021-02528-3
2021
Xiao W; Ren L; Chen Z; Fang LT; Zhao Y; Lack J; Guan M; Zhu B; Jaeger E; Kerrigan L; Blomquist TM; Hung T; Sultan M; Idler K; Lu C; Scherer A; Kusko R; Moos M; Xiao C; Sherry ST; Abaan OD; Chen W; Chen X; Nordlund J; Liljedahl U; Maestro R; Polano M; Drabek J; Vojta P; Kõks S; Reimann E; Madala BS; Mercer T; Miller C; Jacob H; Truong T; Moshrefi A; Natarajan A; Granat A; Schroth GP; Kalamegham R; Peters E; Petitjean V; Walton A; Shen TW; Talsania K; Vera CJ; Langenbach K; de Mars M; Hipp JA; Willey JC; Wang J; Shetty J; Kriga Y; Raziuddin A; Tran B; Zheng Y; Yu Y; Cam M; Jailwala P; Nguyen C; Meerzaman D; Chen Q; Yan C; Ernest B; Mehra U; Jensen RV; Jones W; Li JL; Papas BN; Pirooznia M; Chen YC; Seifuddin F; Li Z; Liu X; Resch W; Wang J; Wu L; Yavas G; Miles C; Ning B; Tong W; Mason CE; Donaldson E; Lababidi S; Staudt LM; Tezak Z; Hong H; Wang C; Shi L, 2021, 'Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing', Nature Biotechnology, 39, pp. 1141 - 1150, http://dx.doi.org/10.1038/s41587-021-00994-5
2021
Mercer TR; Salit M, 2021, 'Testing at scale during the COVID-19 pandemic', Nature Reviews Genetics, 22, pp. 415 - 426, http://dx.doi.org/10.1038/s41576-021-00360-w
2021
Troskie RL; Jafrani Y; Mercer TR; Ewing AD; Faulkner GJ; Cheetham SW, 2021, 'Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome', Genome Biology, 22, http://dx.doi.org/10.1186/s13059-021-02369-0
2021
Madala BS; Reis ALM; Deveson IW; Rawlinson W; Mercer TR, 2021, 'Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-81760-0
2021
Gong B; Li D; Kusko R; Novoradovskaya N; Zhang Y; Wang S; Pabón-Peña C; Zhang Z; Lai K; Cai W; LoCoco JS; Lader E; Richmond TA; Mittal VK; Liu LC; Johann DJ; Willey JC; Bushel PR; Yu Y; Xu C; Chen G; Burgess D; Cawley S; Giorda K; Haseley N; Qiu F; Wilkins K; Arib H; Attwooll C; Babson K; Bao L; Bao W; Lucas AB; Best H; Bhandari A; Bisgin H; Blackburn J; Blomquist TM; Boardman L; Burgher B; Butler DJ; Chang CJ; Chaubey A; Chen T; Chierici M; Chin CR; Close D; Conroy J; Coleman JC; Craig DJ; Crawford E; del Pozo A; Deveson IW; Duncan D; Eterovic AK; Fan X; Foox J; Furlanello C; Ghosal A; Glenn S; Guan M; Haag C; Hang X; Happe S; Hennigan B; Hipp J; Hong H; Horvath K; Hu J; Hung LY; Jarosz M; Kerkhof J; Kipp B; Kreil DP; Łabaj P; Lapunzina P; Li P; Li QZ; Li W; Li Z; Liang Y; Liu S; Liu Z; Ma C; Marella N; Martín-Arenas R; Megherbi DB; Meng Q; Mieczkowski PA; Morrison T; Muzny D; Ning B; Parsons BL; Paweletz CP; Pirooznia M; Qu W; Raymond A; Rindler P; Ringler R; Sadikovic B; Mercer T; Thomas D, 2021, 'Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions', Genome Biology, 22, pp. 109, http://dx.doi.org/10.1186/s13059-021-02315-0
2021
Deveson IW; Gong B; Lai K; LoCoco JS; Richmond TA; Schageman J; Zhang Z; Novoradovskaya N; Willey JC; Jones W; Kusko R; Chen G; Madala BS; Blackburn J; Stevanovski I; Bhandari A; Close D; Conroy J; Hubank M; Marella N; Mieczkowski PA; Qiu F; Sebra R; Stetson D; Sun L; Szankasi P; Tan H; Tang LY; Arib H; Best H; Burgher B; Bushel PR; Casey F; Cawley S; Chang CJ; Choi J; Dinis J; Duncan D; Eterovic AK; Feng L; Ghosal A; Giorda K; Glenn S; Happe S; Haseley N; Horvath K; Hung LY; Jarosz M; Kushwaha G; Li D; Li QZ; Li Z; Liu LC; Liu Z; Ma C; Mason CE; Megherbi DB; Morrison T; Pabón-Peña C; Pirooznia M; Proszek PZ; Raymond A; Rindler P; Ringler R; Scherer A; Shaknovich R; Shi T; Smith M; Song P; Strahl M; Thodima VJ; Tom N; Verma S; Wang J; Wu L; Xiao W; Xu C; Yang M; Zhang G; Zhang S; Zhang Y; Shi L; Tong W; Johann DJ; Mercer TR; Xu J, 2021, 'Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology', Nature Biotechnology, 39, pp. 1115 - 1128, http://dx.doi.org/10.1038/s41587-021-00857-z
2021
Willey JC; Morrison TB; Austermiller B; Crawford EL; Craig DJ; Blomquist TM; Jones WD; Wali A; Lococo JS; Haseley N; Richmond TA; Novoradovskaya N; Kusko R; Chen G; Li QZ; Johann DJ; Deveson IW; Mercer TR; Wu L; Xu J, 2021, 'Advancing NGS quality control to enable measurement of actionable mutations in circulating tumor DNA', Cell Reports Methods, 1, http://dx.doi.org/10.1016/j.crmeth.2021.100106
2021
Fang LT; Zhu B; Zhao Y; Chen W; Yang Z; Kerrigan L; Langenbach K; de Mars M; Lu C; Idler K; Jacob H; Zheng Y; Ren L; Yu Y; Jaeger E; Schroth GP; Abaan OD; Talsania K; Lack J; Shen TW; Chen Z; Stanbouly S; Tran B; Shetty J; Kriga Y; Meerzaman D; Nguyen C; Petitjean V; Sultan M; Cam M; Mehta M; Hung T; Peters E; Kalamegham R; Sahraeian SME; Mohiyuddin M; Guo Y; Yao L; Song L; Lam HYK; Drabek J; Vojta P; Maestro R; Gasparotto D; Köks S; Reimann E; Scherer A; Nordlund J; Liljedahl U; Jensen RV; Pirooznia M; Li Z; Xiao C; Sherry ST; Kusko R; Moos M; Donaldson E; Tezak Z; Ning B; Tong W; Li J; Duerken-Hughes P; Catalanotti C; Maheshwari S; Shuga J; Liang WS; Keats J; Adkins J; Tassone E; Zismann V; McDaniel T; Trent J; Foox J; Butler D; Mason CE; Hong H; Shi L; Wang C; Xiao W; Ashby M; Aygun O; Bian X; Blomquist TM; Bushel P; Campagne F; Chen Q; Chen T; Chen X; Chen YC; Chuang HY; Deng Y; Ernest B; Freed D; Giresi P, 2021, 'Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing', Nature Biotechnology, 39, pp. 1151 - 1160, http://dx.doi.org/10.1038/s41587-021-00993-6
2021
Singh M; Jackson KJL; Wang JJ; Schofield P; Field MA; Koppstein D; Peters TJ; Burnett DL; Rizzetto S; Nevoltris D; Masle-Farquhar E; Faulks ML; Russell A; Gokal D; Hanioka A; Horikawa K; Colella AD; Chataway TK; Blackburn J; Mercer TR; Langley DB; Goodall DM; Jefferis R; Gangadharan Komala M; Kelleher AD; Suan D; Rischmueller M; Christ D; Brink R; Luciani F; Gordon TP; Goodnow CC; Reed JH, 2020, 'Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody', Cell, 180, pp. 878 - 894.e19, http://dx.doi.org/10.1016/j.cell.2020.01.029
2020
Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J; O'Toole S, 2020, 'Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)', Nature Communications, 11, pp. 1810, http://dx.doi.org/10.1038/s41467-020-15697-9
2020
Reis ALM; Deveson IW; Wong T; Madala BS; Barker C; Blackburn J; Marcellin E; Mercer TR, 2020, 'A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-17445-5
2020
Trahair T; Gifford AJ; Fordham A; Mayoh C; Fadia M; Lukeis R; Wood AC; Valvi S; Walker RD; Blackburn J; Heyer EE; Mercer TR; Barbaric D; Marshall GM; MacKenzie KL, 2019, 'Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors', JCO Precision Oncology, 3, pp. 1 - 11, http://dx.doi.org/10.1200/PO.18.00297
2019
Santini NS; Lovelock CE; Hua Q; Zawadzki A; Mazumder D; Mercer TR; Muñoz-Rojas M; Hardwick SA; Madala BS; Cornwell W; Thomas T; Marzinelli EM; Adam P; Paul S; Vergés A; Munoz-Rojas M, 2019, 'Natural and Regenerated Saltmarshes Exhibit Similar Soil and Belowground Organic Carbon Stocks, Root Production and Soil Respiration', Ecosystems, 22, pp. 1803 - 1822, http://dx.doi.org/10.1007/s10021-019-00373-x
2019
Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J; O'Toole S, 2019, 'Diagnosis of fusion genes using targeted RNA sequencing', Nature Communications, 10, pp. 1388, http://dx.doi.org/10.1038/s41467-019-09374-9
2019
Deveson IW; Madala BS; Blackburn J; Barker C; Wong T; Barton KM; Smith MA; Watkins DN; Mercer TR, 2019, 'Chiral DNA sequences as commutable controls for clinical genomics', Nature Communications, 10, http://dx.doi.org/10.1038/s41467-019-09272-0
2019
Blackburn J; Wong T; Madala BS; Barker C; Hardwick SA; Reis ALM; Deveson IW; Mercer TR, 2019, 'Use of synthetic DNA spike-in controls (sequins) for human genome sequencing', Nature Protocols, 14, pp. 2119 - 2151, http://dx.doi.org/10.1038/s41596-019-0175-1
2019
Blackburn J; Vecchiarelli S; Heyer EE; Patrick SM; Lyons RJ; Jaratlerdsiri W; van Zyl S; Bornman MSR; Mercer TR; Hayes VM, 2019, 'TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: A focus on Africa', Prostate, 79, pp. 1191 - 1196, http://dx.doi.org/10.1002/pros.23823
2019
Hardwick SA; Bassett SD; Kaczorowski D; Blackburn J; Barton K; Bartonicek N; Carswell SL; Tilgner HU; Loy C; Halliday G; Mercer TR; Smith MA; Mattick JS, 2019, 'Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions', Frontiers in Genetics, 10, pp. 309, http://dx.doi.org/10.3389/fgene.2019.00309
2019
Signal B; Gloss BS; Dinger ME; Mercer TR, 2018, 'Machine learning annotation of human branchpoints', Bioinformatics, 34, pp. 920 - 927, http://dx.doi.org/10.1093/bioinformatics/btx688
2018
Deveson I; Madala BS; Blackburn J; Barker C; Wong T; Barton K; Smith M; Watkins N; Mercer T, 2018, 'Chiral DNA sequences as commutable reference standards for clinical genomics', BIORXIV, http://dx.doi.org/10.1101/404285
2018
Deveson IW; Brunck ME; Blackburn J; Tseng E; Hon T; Clark TA; Clark MB; Crawford J; Dinger ME; Nielsen LK; Mattick JS; Mercer TR, 2018, 'Universal Alternative Splicing of Noncoding Exons', Cell Systems, 6, pp. 245 - 255.e5, http://dx.doi.org/10.1016/j.cels.2017.12.005
2018
Sowlati T; Sarkar S; Perumana BG; Chan WL; Papio Toda A; Afshar B; Boers M; Shin D; Mercer TR; Chen WH; Grau Besoli A; Yoon S; Kyriazidou S; Yang P; Aggarwal V; Vakilian N; Rozenblit D; Kahrizi M; Zhang J; Wang A; Sen P; Murphy D; Sajjadi A; Mehrabani A; Kornaros E; Low K; Kimura K; Roussel V; Xie H; Kodavati V, 2018, 'A 60-GHz 144-element phased-array transceiver for backhaul application', IEEE Journal of Solid-State Circuits, 53, pp. 3640 - 3659, http://dx.doi.org/10.1109/JSSC.2018.2874048
2018
Hardwick SA; Chen WY; Wong T; Kanakamedala BS; Deveson IW; Ongley SE; Santini NS; Marcellin E; Smith MA; Nielsen LK; Lovelock CE; Neilan BA; Mercer TR, 2018, 'Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-05555-0
2018
Fleuren EDG; Vlenterie M; Van Der Graaf WTA; Hillebrandt-Roeffen MHS; Blackburn J; Ma X; Chan H; Magias MC; Van Erp A; Van Houdt L; Cebeci SAS; Van De Ven A; Flucke UE; Heyer EE; Thomas DM; Lord CJ; Marini KD; Vaghjiani V; Mercer TR; Cain JE; Wu J; Versleijen-Jonkers YMH; Daly RJ, 2017, 'Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes', Cancer Research, 77, pp. 4279 - 4292, http://dx.doi.org/10.1158/0008-5472.CAN-16-2550
2017
Hardwick SA; Deveson IW; Mercer TR, 2017, 'Reference standards for next-generation sequencing', Nature Reviews Genetics, 18, pp. 473 - 484, http://dx.doi.org/10.1038/nrg.2017.44
2017
Bartonicek N; Clark MB; Quek XC; Torpy JR; Pritchard AL; Maag JLV; Gloss BS; Crawford J; Taft RJ; Hayward NK; Montgomery GW; Mattick JS; Mercer TR; Dinger ME, 2017, 'Intergenic disease-associated regions are abundant in novel transcripts', Genome Biology, 18, pp. 241, http://dx.doi.org/10.1186/s13059-017-1363-3
2017
Wong T; Deveson IW; Hardwick SA; Mercer TR, 2017, 'ANAQUIN: A software toolkit for the analysis of spike-in controls for next generation sequencing', Bioinformatics, 33, pp. 1723 - 1724, http://dx.doi.org/10.1093/bioinformatics/btx038
2017
Deveson IW; Hardwick SA; Mercer TR; Mattick JS, 2017, 'The Dimensions, Dynamics, and Relevance of the Mammalian Noncoding Transcriptome', Trends in Genetics, 33, pp. 464 - 478, http://dx.doi.org/10.1016/j.tig.2017.04.004
2017
Betts JA; Moradi Marjaneh M; Al-Ejeh F; Lim YC; Shi W; Sivakumaran H; Tropée R; Patch AM; Clark MB; Bartonicek N; Wiegmans AP; Hillman KM; Kaufmann S; Bain AL; Gloss BS; Crawford J; Kazakoff S; Wani S; Wen SW; Day B; Möller A; Cloonan N; Pearson J; Brown MA; Mercer TR; Waddell N; Khanna KK; Dray E; Dinger ME; Edwards SL; French JD, 2017, 'Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage', American Journal of Human Genetics, 101, pp. 255 - 266, http://dx.doi.org/10.1016/j.ajhg.2017.07.007
2017
Hardwick SA; Chen WY; Wong T; Deveson IW; Blackburn J; Andersen SB; Nielsen LK; Mattick JS; Mercer TR, 2016, 'Spliced synthetic genes as internal controls in RNA sequencing experiments', Nature Methods, 13, pp. 792 - 798, http://dx.doi.org/10.1038/nmeth.3958
2016
Bussotti G; Leonardi T; Clark MB; Mercer TR; Crawford J; Malquori L; Notredame C; Dinger ME; Mattick JS; Enright AJ, 2016, 'Improved definition of the mouse transcriptome via targeted RNA sequencing', Genome Research, 26, pp. 705 - 716, http://dx.doi.org/10.1101/gr.199760.115
2016
Deveson IW; Chen WY; Wong T; Hardwick SA; Andersen SB; Nielsen LK; Mattick JS; Mercer TR, 2016, 'Representing genetic variation with synthetic DNA standards', Nature Methods, 13, pp. 784 - 791, http://dx.doi.org/10.1038/nmeth.3957
2016
Roadmap Epigenomics Consortium ; Kundaje A; Meuleman W; Ernst J; Bilenky M; Yen A; Heravi-Moussavi A; Kheradpour P; Zhang Z; Wang J; Ziller MJ; Amin V; Whitaker JW; Schultz MD; Ward LD; Sarkar A; Quon G; Sandstrom RS; Eaton ML; Wu YC; Pfenning AR; Wang X; Claussnitzer M; Liu Y; Coarfa C; Harris RA; Shoresh N; Epstein CB; Gjoneska E; Leung D; Xie W; Hawkins RD; Lister R; Hong C; Gascard P; Mungall AJ; Moore R; Chuah E; Tam A; Canfield TK; Hansen RS; Kaul R; Sabo PJ; Bansal MS; Carles A; Dixon JR; Farh KH; Feizi S; Karlic R; Kim AR; Kulkarni A; Li D; Lowdon R; Elliott G; Mercer TR; Neph SJ; Onuchic V; Polak P; Rajagopal N; Ray P; Sallari RC; Siebenthall KT; Sinnott-Armstrong NA; Stevens M; Thurman RE; Wu J; Zhang B; Zhou X; Beaudet AE; Boyer LA; De Jager PL; Farnham PJ; Fisher SJ; Haussler D; Jones SJM; Li W; Marra MA; McManus MT; Sunyaev S; Thomson JA; Tlsty TD; Tsai LH; Wang W; Waterland RA; Zhang MQ; Chadwick LH; Bernstein BE; Costello JF; Ecker JR; Hirst M; Meissner A; Milosavljevic A; Ren B; Stamatoyannopoulos JA; Wang T; Kellis M, 2015, 'Integrative analysis of 111 reference human epigenomes', Nature, 518, pp. 317 - 329, http://dx.doi.org/10.1038/nature14248
2015
Mercer TR; Clark MB; Andersen SB; Brunck ME; Haerty W; Crawford J; Taft RJ; Nielsen LK; Dinger ME; Mattick JS, 2015, 'Genome-wide discovery of human splicing branchpoints', Genome Research, 25, pp. 290 - 303, http://dx.doi.org/10.1101/gr.182899.114
2015
Clark MB; Mercer TR; Bussotti G; Leonardi T; Haynes KR; Crawford J; Brunck ME; Cao KAL; Thomas GP; Chen WY; Taft RJ; Nielsen LK; Enright AJ; Mattick JS; Dinger ME, 2015, 'Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing', Nature Methods, 12, pp. 339 - 342, http://dx.doi.org/10.1038/nmeth.3321
2015
Cossetti C; Iraci N; Mercer TR; Leonardi T; Alpi E; Drago D; Alfaro-Cervello C; Saini HK; Davis MP; Schaeffer J; Vega B; Stefanini M; Zhao CJ; Muller W; Garcia-Verdugo JM; Mathivanan S; Bachi A; Enright AJ; Mattick JS; Pluchino S, 2014, 'Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells', Molecular Cell, 56, pp. 609, http://dx.doi.org/10.1016/j.molcel.2014.11.009
2014
Cossetti C; Iraci N; Mercer TR; Leonardi T; Alpi E; Drago D; Alfaro-Cervello C; Saini HK; Davis MP; Schaeffer J; Vega B; Stefanini M; Zhao CJ; Muller W; Garcia-Verdugo JM; Mathivanan S; Bachi A; Enright AJ; Mattick JS; Pluchino S, 2014, 'Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells', Molecular Cell, 56, pp. 193 - 204, http://dx.doi.org/10.1016/j.molcel.2014.08.020
2014
Mercer TR; Clark MB; Crawford J; Brunck ME; Gerhardt DJ; Taft RJ; Nielsen LK; Dinger ME; Mattick JS, 2014, 'Targeted sequencing for gene discovery and quantification using RNA CaptureSeq', Nature Protocols, 9, pp. 989 - 1009, http://dx.doi.org/10.1038/nprot.2014.058
2014
Marcellin E; Mercer TR; Licona-Cassani C; Palfreyman RW; Dinger ME; Steen JA; Mattick JS; Nielsen LK, 2013, 'Saccharopolyspora erythraea’s genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch', BMC Genomics, 14, pp. 15 - 25, http://dx.doi.org/10.1186/1471-2164-14-15
2013
Mercer TR; Mattick JS, 2013, 'Structure and function of long noncoding RNAs in epigenetic regulation', Nature Structural & Molecular Biology, 20, pp. 300 - 307, http://dx.doi.org/10.1038/nsmb.2480
2013
Marcellin E; Licona-Cassani C; Mercer TR; Palfreyman RW; Nielsen LK, 2013, 'Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach', BMC Genomics, 14, http://dx.doi.org/10.1186/1471-2164-14-699
2013
Liu G; Mercer TR; Shearwood AMJ; Siira SJ; Hibbs ME; Mattick JS; Rackham O; Filipovska A, 2013, 'Mapping of mitochondrial RNA-protein interactions by digital rnase footprinting', Cell Reports, 5, pp. 839 - 848, http://dx.doi.org/10.1016/j.celrep.2013.09.036
2013
Mercer TR; Edwards SL; Clark MB; Neph SJ; Wang H; Stergachis AB; John S; Sandstrom R; Li G; Sandhu KS; Ruan Y; Nielsen LK; Mattick JS; Stamatoyannopoulos JA, 2013, 'DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements', Nature Genetics, 45, pp. 852 - 859, http://dx.doi.org/10.1038/ng.2677
2013
Mercer TR; Mattick JS, 2013, 'Understanding the regulatory and transcriptional complexity of the genome through structure', Genome Research, 23, pp. 1081 - 1088, http://dx.doi.org/10.1101/gr.156612.113
2013
Mercer TR; Gerhardt DJ; Dinger ME; Crawford J; Trapnell C; Jeddeloh JA; Mattick JS; Rinn JL, 2012, 'Targeted RNA sequencing reveals the deep complexity of the human transcriptome', Nature Biotechnology, 30, pp. 99 - 104, http://dx.doi.org/10.1038/nbt.2024
2012
Cruickshank MN; Karimi M; Mason RL; Fenwick E; Mercer T; Tsao BP; Boackle SA; Ulgiati D, 2012, 'Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21)', Molecular Immunology, 52, pp. 165 - 173, http://dx.doi.org/10.1016/j.molimm.2012.04.013
2012
Rackham O; Mercer TR; Filipovska A, 2012, 'The human mitochondrial transcriptome and the rna-binding proteins that regulate its expression', Wiley Interdisciplinary Reviews: RNA, 3, pp. 675 - 695, http://dx.doi.org/10.1002/wrna.1128
2012
Thiagarajan RD; Cloonan N; Gardiner BB; Mercer TR; Kolle G; Nourbakhsh E; Wani S; Tang D; Krishnan K; Georgas KM; Rumballe BA; Chiu HS; Steen JA; Mattick JS; Little MH; Grimmond SM, 2011, 'Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling', BMC Genomics, 12, http://dx.doi.org/10.1186/1471-2164-12-441
2011
Mercer TR; Neph S; Dinger ME; Crawford J; Smith MA; Shearwood AMJ; Haugen E; Bracken CP; Rackham O; Stamatoyannopoulos JA; Filipovska A; Mattick JS, 2011, 'The human mitochondrial transcriptome', Cell, 146, pp. 645 - 658, http://dx.doi.org/10.1016/j.cell.2011.06.051
2011
Rackham O; Shearwood AMJ; Mercer TR; Davies SMK; Mattick JS; Filipovska A, 2011, 'Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins', RNA, 17, pp. 2085 - 2093, http://dx.doi.org/10.1261/rna.029405.111
2011
Mercer TR; Wilhelm D; Dinger ME; Soldà G; Korbie DJ; Glazov EA; Truong V; Schwenke M; Simons C; Matthaei KI; Saint R; Koopman P; Mattick JS, 2011, 'Expression of distinct RNAs from 3′ untranslated regions', Nucleic Acids Research, 39, pp. 2393 - 2403, http://dx.doi.org/10.1093/nar/gkq1158
2011
Bracken CP; Szubert JM; Mercer TR; Dinger ME; Thomson DW; Mattick JS; Michael MZ; Goodall GJ, 2011, 'Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage', Nucleic Acids Research, 39, pp. 5658 - 5668, http://dx.doi.org/10.1093/nar/gkr110
2011
Lopez Sanchez MIG; Mercer TR; Davies SMK; Shearwood AMJ; Nygård KKA; Richman TR; Mattick JS; Rackham O; Filipovska A, 2011, 'RNA processing in human mitochondria', Cell Cycle, 10, pp. 2904 - 2916, http://dx.doi.org/10.4161/cc.10.17.17060
2011
Askarian-Amiri ME; Crawford J; French JD; Smart CE; Smith MA; Clark MB; Ru K; Mercer TR; Thompson ER; Lakhani SR; Vargas AC; Campbell IG; Brown MA; Dinger ME; Mattick JS, 2011, 'SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer', RNA, 17, pp. 878 - 891, http://dx.doi.org/10.1261/rna.2528811
2011
Taft RJ; Simons C; Nahkuri S; Oey H; Korbie DJ; Mercer TR; Holst J; Ritchie W; Wong JJL; Rasko JEJ; Rokhsar DS; Degnan BM; Mattick JS, 2010, 'Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans', Nature Structural and Molecular Biology, 17, pp. 1030 - 1034, http://dx.doi.org/10.1038/nsmb.1841
2010
Taft RJ; Pang KC; Mercer TR; Dinger M; Mattick JS, 2010, 'Non-coding RNAs: Regulators of disease', Journal of Pathology, 220, pp. 126 - 139, http://dx.doi.org/10.1002/path.2638
2010
Mercer TR; Qureshi IA; Gokhan S; Dinger ME; Li G; Mattick JS; Mehler MF, 2010, 'Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation', BMC Neuroscience, 11, http://dx.doi.org/10.1186/1471-2202-11-14
2010
Lai J; Lehman ML; Dinger ME; Hendy SC; Mercer TR; Seim I; Lawrence MG; Mattick JS; Clements JA; Nelson CC, 2010, 'A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells', RNA, 16, pp. 1156 - 1166, http://dx.doi.org/10.1261/rna.2019810
2010
Mercer TR; Dinger ME; Bracken CP; Kolle G; Szubert JM; Korbie DJ; Askarian-Amiri ME; Gardiner BB; Goodall GJ; Grimmond SM; Mattick JS, 2010, 'Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome', Genome Research, 20, pp. 1639 - 1650, http://dx.doi.org/10.1101/gr.112128.110
2010
Mattick JS; Amaral PP; Dinger ME; Mercer TR; Mehler MF, 2009, 'RNA regulation of epigenetic processes', BioEssays, 31, pp. 51 - 59, http://dx.doi.org/10.1002/bies.080099
2009
Pang KC; Dinger ME; Mercer TR; Malquori L; Grimmond SM; Chen W; Mattick JS, 2009, 'Genome-wide identification of long noncoding RNAs in CD8+ T cells', Journal of Immunology, 182, pp. 7738 - 7748, http://dx.doi.org/10.4049/jimmunol.0900603
2009
Mercer TR; Dinger ME; Mattick JS, 2009, 'Long non-coding RNAs: Insights into functions', Nature Reviews Genetics, 10, pp. 155 - 159, http://dx.doi.org/10.1038/nrg2521
2009
Dinger ME; Amaral PP; Mercer TR; Mattick JS, 2009, 'Pervasive transcription of the eukaryotic genome: Functional indices and conceptual implications', Briefings in Functional Genomics and Proteomics, 8, pp. 407 - 423, http://dx.doi.org/10.1093/bfgp/elp038
2009
Dinger ME; Pang KC; Mercer TR; Crowe ML; Grimmond SM; Mattick JS, 2009, 'NRED: A database of long noncoding RNA expression', Nucleic Acids Research, 37, http://dx.doi.org/10.1093/nar/gkn617
2009
Amaral PP; Dinger ME; Mercer TR; Mattick JS, 2008, 'The eukaryotic genome as an RNA machine', Science, 319, pp. 1787 - 1789, http://dx.doi.org/10.1126/science.1155472
2008
Mattick JS; Croft LJ; Pheasant M; Mercer TR; Dinger ME, 2008, 'The mammalian genome as an RNA machine', FASEB JOURNAL, 22, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208467805697&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2008
Mercer TR; Dinger ME; Sunkin SM; Mehler MF; Mattick JS, 2008, 'Specific expression of long noncoding RNAs in the mouse brain', Proceedings of the National Academy of Sciences of the United States of America, 105, pp. 716 - 721, http://dx.doi.org/10.1073/pnas.0706729105
2008
Dinger ME; Amara PP; Mercer TR; Pang KC; Bruce SJ; Gardiner BB; Askarian-Amiri ME; Ru K; Soldà G; Simons C; Sunkin SM; Crowe ML; Grimmond SM; Perkins AC; Mattick JS, 2008, 'Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation', Genome Research, 18, pp. 1433 - 1445, http://dx.doi.org/10.1101/gr.078378.108
2008
Mercer TR; Dinger ME; Mariani J; Kosik KS; Mehler MF; Mattick JS, 2008, 'Noncoding RNAs in long-term memory formation', Neuroscientist, 14, pp. 434 - 445, http://dx.doi.org/10.1177/1073858408319187
2008
Dinger ME; Pang KC; Mercer TR; Mattick JS, 2008, 'Differentiating protein-coding and noncoding RNA: Challenges and ambiguities', PLoS Computational Biology, 4, http://dx.doi.org/10.1371/journal.pcbi.1000176
2008
Dinger ME; Mercer TR; Mattick JS, 2008, 'RNAs as extracellular signaling molecules', Journal of Molecular Endocrinology, 40, pp. 151 - 159, http://dx.doi.org/10.1677/JME-07-0160
2008
Wu H; Boackle SA; Hanvivadhanakul P; Ulgiati D; Grossman JM; Lee Y; Shen N; Abraham LJ; Mercer TR; Park E; Hebert LA; Rovin BH; Birmingham DJ; Chang DM; Chung JC; McCurdy D; Badsha HM; Thong BYH; Chng HH; Arnett FC; Wallace DJ; Yu CY; Hahn BH; Cantor RM; Tsao BP, 2007, 'Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 3961 - 3966, http://dx.doi.org/10.1073/pnas.0609101104
2007
Preprints
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Giles K; Phipps A; Cashion J; Huskins S; Mercer T; Robinson M; Woodhouse A; Taberlay P, 2022, H3K4me3 enrichment defines neuronal age, while a youthful H3K27ac signature is recapitulated in aged neurons, , http://dx.doi.org/10.21203/rs.3.rs-1367459/v1
2022
Williams T; Kroukamp H; Xu X; Wightman E; Llorente B; Borneman A; Carpenter A; Van Wyk N; Espinosa M; Daniel E; Walker R; Cai Y; Nevalainen H; Curach N; Deveson I; Mercer T; Johnson D; Mitchell L; Bader J; Stracquadanio G; Boeke J; Goold H; Pretorius I; Paulsen I, 2022, Laboratory evolution and polyploid SCRaMbLE reveal genomic plasticity to synthetic chromosome defects and rearrangements, , http://dx.doi.org/10.1101/2022.07.22.501046
2022
Giles K; Phipps A; Cashion J; Huskins S; Mercer T; Robinson M; Woodhouse A; Taberlay P, 2021, H3K4me3 enrichment defines neuronal age, while a youthful H3K27ac signature is recapitulated in aged neurons, , http://dx.doi.org/10.1101/2021.11.11.467877
2021
Li X; Zhao Q; Wang Z; Liau W-S; Basic D; Ren H; Marshall PR; Zajaczkowski EL; Leighton LJ; Madugalle SU; Musgrove M; Periyakaruppiah A; Shi J; Zhang J; Mattick JS; Mercer TR; Wei W; Bredy TW, 2021, On the discovery of ADRAM, an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3, , http://dx.doi.org/10.1101/2021.08.01.454607
2021
Signal B; Gloss BS; Dinger ME; Mercer TR, 2016, Machine-learning annotation of human splicing branchpoints, , http://dx.doi.org/10.1101/094003
2016
Conference Papers
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Sowlati T; Sarkar S; Perumana B; Chan WL; Afshar B; Boers M; Shin D; Mercer T; Chen WH; Toda AP; Besoli AG; Yoon S; Kyriazidou S; Yang P; Aggarwal V; Vakilian N; Rozenblit D; Kahrizi M; Zhang J; Wang A; Sen P; Murphy D; Mikhemar M; Sajjadi A; Mehrabani A; Ibrahim B; Pan B; Juan K; Xu S; Guan C; Geshvindman G; Low K; Kocaman N; Eberhart H; Kimura K; Elgorriaga I; Roussel V; Xie H; Shi L; Kodavati V, 2018, 'A 60GHz 144-element phased-array transceiver with 51dBm maximum EIRP and ±60° beam steering for backhaul application', in Digest of Technical Papers - IEEE International Solid-State Circuits Conference, pp. 66 - 68, http://dx.doi.org/10.1109/ISSCC.2018.8310186
2018
Clark MB; Mercer TR; Leonardi T; Bussotti G; Crawford J; Nielsen LK; Enright AJ; Ponting CP; Dinger ME; Mattick JS, 2014, 'Quantitative gene expression profiling with targeted RNA sequencing', in FEBS JOURNAL, WILEY-BLACKWELL, FRANCE, Paris, pp. 45 - 45, presented at FEBS EMBO 2014 Conference, FRANCE, Paris, 30 August 2014 - 04 September 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000359666800141&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Iraci N; Cossetti C; Mercer T; Leonardi T; Alpi E; Drago D; Alfaro-cervello C; Saini H; Davis M; Schaeffer J; Muller W; Manuel Garcia-verdugo J; Mathivanan S; Bachi A; Enright A; Mattick J; Pluchino S, 2014, 'Extracellular vesicles from neural stem cells transfer the IFN-gamma/IFNGR1 complex to activate Stat1-dependent signalling in target cells', in JOURNAL OF NEUROIMMUNOLOGY, ELSEVIER SCIENCE BV, GERMANY, Mainz, pp. 190 - 191, presented at 12th International Congress of Neuroimmunology (ISNI), GERMANY, Mainz, 09 November 2014 - 13 November 2014, http://dx.doi.org/10.1016/j.jneuroim.2014.08.513
2014
Analui B; Mercer T; Mandegaran S; Goel A; Hashemi H, 2014, 'A 50 MHz-6 GHz, 2 × 2 MIMO, reconfigurable architecture, software-defined radio in 130nm CMOS', in Digest of Papers - IEEE Radio Frequency Integrated Circuits Symposium, pp. 329 - 332, http://dx.doi.org/10.1109/RFIC.2014.6851733
2014
Chu TS; Roderick J; Chang SH; Mercer T; Du C; Hashemi H, 2011, 'A short-range UWB impulse-radio CMOS sensor for human feature detection', in Digest of Technical Papers - IEEE International Solid-State Circuits Conference, pp. 294 - 295, http://dx.doi.org/10.1109/ISSCC.2011.5746325
2011
Chang SH; Chu TS; Roderick J; Du C; Mercer T; Burdick JW; Hashemi H, 2011, 'UWB human detection radar system: A RF CMOS chip and algorithm integrated sensor', in Proceedings - IEEE International Conference on Ultra-Wideband, pp. 355 - 359, http://dx.doi.org/10.1109/ICUWB.2011.6058863
2011