John Murray

Emeritus Professor

My research covers mathematical modelling of infectious diseases and the complex dynamical systems of their interaction in vivo with the immune system, as well as the epidemiology of their spread through communities. I collaborate with biomedical groups in Australia and overseas, particularly related to human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). 

Education

  • Ph D, Applied Mathematics, University of Washington, Seattle, USA, 1984
  • M Sc, Applied Mathematics, University of New South Wales, Sydney, Australia, 1978
  • B Sc (hons), Applied Mathematics, University of New South Wales, Sydney, Australia, 1976 

RESEARCH INTERESTS

  • Mathematical Modeling of Infectious Diseases 
  • Biomathematics 
  • Epidemiology

Recent Research Grants

  • UNSW Cellular Genomics Futures Institute 2020 Seed Funding, "Predicting Time to Environment-Dependent Emergence of Multiple Myeloma in Patients (PreEEmpt), Croucher, Murray, Pagnucco, Moore, Phan, 2020-2022.
  • ARC Discovery Project, "Determining features that separate groups of protein sequences", Murray, 2018-2020.
  • NHMRC Project Grant, "Resolving Human Immunodeficiency Virus (HIV) transmission", Turville, Hope, Vallely, MacLaren, Carr, Murray, Liu, 2017-2019.
  • ARC Linkage Grant, “Innovative mathematical modelling to determine incorporation of gene therapy in different cell lineages; Human Immunodeficiency Virus (HIV) as a model setting”, Murray, Symonds, 2013-2016.
  • ARC Discovery Project, "Mathematical modelling can provide vital information on the effectiveness and practical implementation of microbicides and vaccines against HIV", Murray, Henry, Langlands, Klasse, 2013-2015.
  • ARC Linkage Grant, “Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV?”, Murray, Symonds, 2010-2012.
  • NHMRC Project Grant, "Processes underlying establishment and maintenance of the latent HIV reservoir and potential impact of integrase inhibitors", Zaunders, Murray, Suzuki, 2008-2010.
  • Australian Development Research Award, "Evaluating and predicting the epidemiological impact of health policies for reducing HIV in Melanesian and South-East Asian populations", Wilson, Hoare, Murray, Kaldor, Law, 2008-2010.

 

 

PUBLICATIONS
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Journal articles
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Murray JM; Murray DD; Schvoerer E; Akand EH, 2024, 'SARS-CoV-2 Delta and Omicron community transmission networks as added value to contact tracing', Journal of Infection, 88, pp. 173 - 179, http://dx.doi.org/10.1016/j.jinf.2024.01.004
2024
Kyaw W; Chai RC; Khoo WH; Goldstein LD; Croucher PI; Murray JM; Phan TG, 2023, 'ENTRAIN: integrating trajectory inference and gene regulatory networks with spatial data to co-localize the receptor–ligand interactions that specify cell fate', Bioinformatics, 39, http://dx.doi.org/10.1093/bioinformatics/btad765
2023
Hall MT; Simms KT; Murray JM; Keane A; Nguyen DTN; Caruana M; Lui G; Kelly H; Eckert LO; Santesso N; de Sanjose S; Swai EE; Rangaraj A; Owiredu MN; Gauvreau C; Demke O; Basu P; Arbyn M; Dalal S; Broutet N; Canfell K, 2023, 'Benefits and harms of cervical screening, triage and treatment strategies in women living with HIV', Nature Medicine, 29, pp. 3059 - 3066, http://dx.doi.org/10.1038/s41591-023-02601-3
2023
Chaqroun A; Hartard C; Josse T; Taverniers A; Jeulin H; Gantzer C; Murray JM; Bertrand I; Schvoerer E, 2022, 'SARS-CoV-2 Variability in Patients and Wastewaters—Potential Immuno-Modulation during the Shift from Delta to Omicron', Biomedicines, 10, http://dx.doi.org/10.3390/biomedicines10092080
2022
Vaneckova P; Wade S; Weber M; Murray JM; Grogan P; Caruana M; Banks E; Canfell K, 2021, 'Birth-cohort estimates of smoking initiation and prevalence in 20th century Australia: Synthesis of data from 33 surveys and 385,810 participants', PLoS ONE, 16, http://dx.doi.org/10.1371/journal.pone.0250824
2021
Angstmann CN; Erickson AM; Henry BI; McGann AV; Murray JM; Nichols JA, 2021, 'A general framework for fractional order compartment models', SIAM Review, 63, pp. 375 - 392, http://dx.doi.org/10.1137/21M1398549
2021
Bockmann JH; Kohsar M; Murray JM; Hamed V; Dandri M; Lüth S; Lohse AW; Schulze-Zur-wiesch J, 2021, 'High rates of liver cirrhosis and hepatocellular carcinoma in chronic hepatitis b patients with metabolic and cardiovascular comorbidities', Microorganisms, 9, http://dx.doi.org/10.3390/microorganisms9050968
2021
Murray JM, 2021, 'Dynamics of latent HIV under clonal expansion', PLoS Pathogens, 17, http://dx.doi.org/10.1371/journal.ppat.1010165
2021
Akand EH; Murray JM, 2021, 'NGlyAlign: an automated library building tool to align highly divergent HIV envelope sequences', BMC Bioinformatics, 22, http://dx.doi.org/10.1186/s12859-020-03901-y
2021
Hartard C; Fenaux H; Gentilhomme A; Murray JM; Akand E; Laugel E; Berger S; Maul A; de Rougemont A; Jeulin H; Remen T; Bensenane M; Bronowicki JP; Gantzer C; Bertrand I; Schvoerer E, 2021, 'Variability in molecular characteristics of Hepatitis E virus quasispecies could modify viral surface properties and transmission', Journal of Viral Hepatitis, 28, pp. 1078 - 1090, http://dx.doi.org/10.1111/jvh.13513
2021
Hall MT; Smith MA; Simms KT; Barnabas R; Murray JM; Canfell K, 2021, 'Elimination of cervical cancer in Tanzania: Modelled analysis of elimination in the context of endemic HIV infection and active HIV control', International Journal of Cancer, 149, pp. 297 - 306, http://dx.doi.org/10.1002/ijc.33533
2021
Bockmann JH; Grube M; Hamed V; Von Felden J; Landahl J; Wehmeyer M; Giersch K; Hall MT; Murray JM; Dandri M; Lüth S; Lohse AW; Lütgehetmann M; Schulze Zur Wiesch J, 2020, 'High rates of cirrhosis and severe clinical events in patients with HBV/HDV co-infection: longitudinal analysis of a German cohort', BMC Gastroenterology, 20, http://dx.doi.org/10.1186/s12876-020-1168-9
2020
Akand EH; Maher SJ; Murray JM, 2020, 'Mutational networks of escape from transmitted HIV-1 infection', PLoS ONE, 15, http://dx.doi.org/10.1371/journal.pone.0243391
2020
Hall MT; Smith MA; Simms KT; Barnabas RV; Canfell K; Murray JM, 2020, 'The past, present and future impact of HIV prevention and control on HPV and cervical disease in Tanzania: A modelling study', PLoS ONE, 15, http://dx.doi.org/10.1371/journal.pone.0231388
2020
Jeulin H; Jeanmaire E; Murray JM; Malve B; André M; Melliez H; Lanoix JP; Hustache-Mathieu L; Partisani M; Goehringer F; May T; Schvoerer E, 2019, 'Treatment as prevention enrolling at least 75% of individuals on ART will be needed to significantly reduce HIV prevalence in a HIV cohort', Journal of Clinical Virology, 120, pp. 27 - 32, http://dx.doi.org/10.1016/j.jcv.2019.08.010
2019
Murray JM; Ribeiro RM, 2018, 'Special issue “Mathematical modeling of viral infections”', Viruses, 10, http://dx.doi.org/10.3390/v10060303
2018
Ledger S; Howe A; Turville S; Aggarwal A; Savkovic B; Ong A; Wolstein O; Boyd M; Millington M; Gorry PR; Murray JM; Symonds G, 2018, 'Analysis and dissociation of anti-HIV effects of shRNA to CCR5 and the fusion inhibitor C46', Journal of Gene Medicine, 20, http://dx.doi.org/10.1002/jgm.3006
2018
Murray JM, 2018, 'Latent HIV dynamics and implications for sustained viral suppression in the absence of antiretroviral therapy', JOURNAL OF VIRUS ERADICATION, 4, pp. 91 - 98, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000441194200005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Angstmann CN; Erickson AM; Henry BI; McGann A; Murray J; Nichols J, 2017, 'Fractional order compartment models', SIAM Journal on Applied Mathematics, 77, pp. 430 - 446, http://dx.doi.org/10.1137/16M1069249
2017
Murray JM; Maher S; Mota T; Suzuki K; Kelleher AD; Center RJ; Purcell D, 2017, 'Differentiating founder and chronic HIV envelope sequences', PLoS ONE, 12, pp. e0171572, http://dx.doi.org/10.1371/journal.pone.0171572
2017
Goyal A; Murray JM, 2017, 'Roadmap to control HBV and HDV epidemics in China', Journal of Theoretical Biology, 423, pp. 41 - 52, http://dx.doi.org/10.1016/j.jtbi.2017.04.007
2017
Dawson B; Young L; Murray JM; Wilkinson I, 2017, 'Drivers of supplier-customer relationship profitability in China: Assessing International Joint Ventures versus State Owned Enterprises', Industrial Marketing Management, 66, pp. 29 - 41, http://dx.doi.org/10.1016/j.indmarman.2017.06.009
2017
Murray JM; Zaunders J; Emery S; Cooper DA; Hey-Nguyen WJ; Koelsch KK; Kelleher AD, 2017, 'HIV dynamics linked to memory CD4+ T cell homeostasis', PLoS ONE, 12, pp. e0186101, http://dx.doi.org/10.1371/journal.pone.0186101
2017
Zaunders J; Howe A; Ledger S; Kelleher A; Murray J; Symonds G, 2017, '23 Knockdown of CCR5 expression in antigen-specific cytotoxic CD4 T cells', Journal of Virus Eradication, 3, pp. 14 - 15, http://dx.doi.org/10.1016/s2055-6640(20)30728-7
2017
Goyal A; Murray JM, 2016, 'Cost-Effectiveness of Peg-Interferon, Interferon and Oral Nucleoside Analogues in the Treatment of Chronic Hepatitis B and D Infections in China', Clinical Drug Investigation, 36, pp. 637 - 648, http://dx.doi.org/10.1007/s40261-016-0409-8
2016
Goyal A; Murray JM, 2016, 'Dynamics of in vivo hepatitis D virus infection', Journal of Theoretical Biology, 398, pp. 9 - 19, http://dx.doi.org/10.1016/j.jtbi.2016.03.018
2016
Goyal A; Murray JM, 2016, 'Modelling the impact of cell-to-cell transmission in hepatitis B virus', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0161978
2016
Goyal A; Murray JM, 2016, 'Recognizing the impact of endemic hepatitis D virus on hepatitis B virus eradication', Theoretical Population Biology, 112, pp. 60 - 69, http://dx.doi.org/10.1016/j.tpb.2016.08.004
2016
Maher SJ; Murray JM, 2016, 'The unrooted set covering connected subgraph problem differentiating between HIV envelope sequences', European Journal of Operational Research, 248, pp. 668 - 680, http://dx.doi.org/10.1016/j.ejor.2015.07.011
2016
Velay A; Jeulin H; Eschlimann M; Malvé B; Goehringer F; Bensenane M; Frippiat JP; Abraham P; Ismail AM; Murray JM; Combet C; Zoulim F; Bronowicki JP; Schvoerer E, 2016, 'Characterization of hepatitis B virus surface antigen variability and impact on HBs antigen clearance under nucleos(t)ide analogue therapy', Journal of Viral Hepatitis, 23, pp. 387 - 398, http://dx.doi.org/10.1111/jvh.12498
2016
Murray JM; Stancevic O; Lütgehetmann M; Wursthorn K; Petersen J; Dandri M, 2016, 'Variability in long-term hepatitis B virus dynamics under antiviral therapy', Journal of Theoretical Biology, 391, pp. 74 - 80, http://dx.doi.org/10.1016/j.jtbi.2015.12.005
2016
Hey-Cunningham WJ; Murray JM; Natarajan V; Amin J; Moore CL; Emery S; Cooper DA; Zaunders J; Kelleher AD; Koelsch KK; PINT study team ; Danta M, 2015, 'Early antiretroviral therapy with raltegravir generates sustained reductions in HIV reservoirs but not lower T-cell activation levels.', AIDS, 29, pp. 911 - 919, http://dx.doi.org/10.1097/QAD.0000000000000625
2015
Erickson AM; Henry BI; Murray JM; Klasse PJ; Angstmann CN, 2015, 'Predicting First Traversal Times for Virions and Nanoparticles in Mucus with Slowed Diffusion', Biophysical Journal, 109, pp. 164 - 172, http://dx.doi.org/10.1016/j.bpj.2015.05.034
2015
Murray JM; Goyal A, 2015, 'In silico single cell dynamics of hepatitis B virus infection and clearance', Journal of Theoretical Biology, 366, pp. 91 - 102, http://dx.doi.org/10.1016/j.jtbi.2014.11.020
2015
Murray JM; Zaunders JJ; McBride KL; Xu Y; Bailey M; Suzuki K; Cooper DA; Emery S; Kelleher AD; Koelsch KK, 2014, 'HIV DNA subspecies persist in both activated and resting memory CD4+ T cells during antiretroviral therapy', Journal of Virology, 88, pp. 3516 - 3526, http://dx.doi.org/10.1128/JVI.03331-13
2014
Goyal A; Murray JM, 2014, 'Effect of interferon-alfa therapy on hepatitis D virus', Hepatology, pp. n/a - n/a, http://dx.doi.org/10.1002/hep.27595
2014
Vallely A; Ryan CE; Allen J; Sauk JC; Simbiken CS; Wapling J; Kaima P; Kombati Z; Law G; Fehler G; Murray JM; Siba P; Kaldor JM, 2014, 'High prevalence and incidence of HIV, sexually transmissible infections and penile foreskin cutting among sexual health clinic attendees in Papua New Guinea', Sexual Health, 11, pp. 58 - 66, http://dx.doi.org/10.1071/SH13197
2014
Gray RT; Vallely A; Wilson DP; Kaldor J; MacLaren D; Kelly-Hanku A; Siba P; Murray JM, 2014, 'Impact of male circumcision on the HIV epidemic in Papua New Guinea: A country with extensive foreskin cutting practices', PLoS ONE, 9, pp. e104531, http://dx.doi.org/10.1371/journal.pone.0104531
2014
Goyal A; Murray JM, 2014, 'The Impact of Vaccination and Antiviral Therapy on Hepatitis B and Hepatitis D Epidemiology', PLoS ONE, 9, pp. e110143, http://dx.doi.org/10.1371/journal.pone.0110143
2014
Savkovic B; Nichols J; Birkett D; Applegate T; Ledger S; Symonds G; Murray JM, 2014, 'A Quantitative Comparison of Anti-HIV Gene Therapy Delivered to Hematopoietic Stem Cells versus CD4+ T Cells', PLoS Computational Biology, 10, http://dx.doi.org/10.1371/journal.pcbi.1003681
2014
Murray JM; Zaunders JJ; Koelsch KK; Natarajan V; Badralmaa Y; McBride K; Carrera A; Cooper DA; Emery S; Kelleher AD, 2013, 'Short communication: HIV blips while on antiretroviral therapy can indicate consistently detectable viral levels due to assay underreporting', AIDS Research and Human Retroviruses, 29, pp. 1621 - 1625, http://dx.doi.org/10.1089/aid.2013.0132
2013
Murray JM, 2013, 'HIV Treatment as Prevention in a Developed Country Setting: The current situation and future scenarios for Australia', JAIDS Journal of Acquired Immune Deficiency Syndromes, 64, pp. 409 - 416, http://dx.doi.org/10.1097/QAI.0b013e3182a6b20c
2013
McBride K; Xu Y; Bailey M; Seddiki N; Suzuki K; Murray JM; Gao Y; Yan C; Cooper DA; Kelleher AD; Koelsch KK; Zaunders J, 2013, 'The majority of HIV type 1 DNA in circulating CD4+ T lymphocytes is present in non-gut-homing resting memory CD4+ T cells', AIDS Research and Human Retroviruses, 29, pp. 1330 - 1339, http://dx.doi.org/10.1089/aid.2012.0351
2013
Stancevic O; Angstmann CN; Murray JM; Henry B, 2013, 'Turing patterns from dynamics of early HIV infection', Bulletin of Mathematical Biology, 75, pp. 774 - 795, http://dx.doi.org/10.1007/s11538-013-9834-5
2013
Murray JM; Moenne-Loccoz R; Velay A; Habersetzer F; Doffoel M; Gut JP; Fofana I; Zeisel MB; Stoll-keller F; Baumert TF; Schvoerer E, 2013, 'Genotype 1 hepatitis C virus envelope features that determine antiviral response assessed through optimal covariance networks', PLoS ONE, 8, pp. e67254, http://dx.doi.org/10.1371/journal.pone.0067254
2013
Schvoerer E; Moenne-Loccoz R; Murray JM; Velay A; Turek M; Fofana I; Fafi-kremer S; Erba AC; Habersetzer F; Doffoel M; Gut JP; Donlin MJ; Tavis JE; Zeisel MB; Stoll-keller F; Baumert TF, 2013, 'Hepatitis C virus envelope glycoprotein signatures are associated with treatment failure and modulation of viral entry and neutralization', Journal of Infectious Diseases, 207, pp. 1306 - 1315, http://dx.doi.org/10.1093/infdis/jit032
2013
Jeulin H; Velay A; Murray JM; Schvoerer E, 2013, 'Clinical impact of hepatitis B and C virus envelope glycoproteins', World Journal of Gastroenterology, 19, pp. 654 - 664, http://dx.doi.org/10.3748/wjg.v19.i5.654
2013
Gilmore JB; Kelleher AD; Cooper DA; Murray JM, 2013, 'Explaining the determinants of first phase HIV decay dynamics through the effects of stage-dependent drug action', PLoS Computational Biology, 9, pp. e1002971 (11pp), http://dx.doi.org/10.1371/journal.pcbi.1002971
2013
Savkovic B; Symonds G; Murray JM, 2012, 'Stochastic model of in-vivo X4 emergence during HIV infection: implications for the CCR5 inhibitor maraviroc', PLoS ONE, 7, pp. 1 - 14, http://dx.doi.org/10.1371/journal.pone.0038755
2012
Savkovic B; Macpherson JL; Zaunders J; Kelleher A; Knop A; Pond S; Evans L; Symonds G; Murray JM, 2012, 'T-lymphocyte perturbation following large-scale apheresis and hematopoietic stem cell transplantation in HIV-infected individuals', Clinical Immunology, 144, pp. 159 - 171, http://dx.doi.org/10.1016/j.clim.2012.06.004
2012
Shaddock EJ; Richards GA; Murray J, 2012, 'Lung fibrosis in deceased HIV-infected patients with Pneumocystis pneumonia', Southern African Journal of HIV Medicine, 13, pp. 64 - 67, http://dx.doi.org/10.4102/sajhivmed.v13i2.140
2012
Mota T; Murray JM; Center R; Purcell D; McCaw J, 2012, 'Application of a case-control study design to investigate genotypic signatures of HIV-1 transmission', Retrovirology, 9, pp. 54, http://dx.doi.org/10.1186/1742-4690-9-54
2012
Chakrabarty SP; Murray JM, 2012, 'Modelling hepatitis C virus infection and the development of hepatocellular carcinoma', Journal of Theoretical Biology, 305, pp. 24 - 29, http://dx.doi.org/10.1016/j.jtbi.2012.03.030
2012
Murray J; Cutcher L, 2012, 'Gendered futures, constrained choices: Undergraduate perceptions of work and family', Journal of Population Research, 29, pp. 315 - 328, http://dx.doi.org/10.1007/s12546-012-9099-0
2012
Murray JM; McBride K; Boesecke C; Bailey MR; Amin J; Suzuki K; Baker D; Zaunders JJ; Emery S; Cooper DA; Koelsch KK; Kelleher AD, 2012, 'Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards', AIDS, 26, pp. 543 - 550, http://dx.doi.org/10.1097/QAD.0b013e328350fb3c
2012
Murray JM; Ritter A, 2011, 'Findings regarding reduced prevalence with hepatitis C treatment are still valid: a reply to Vickerman et al', Drug and Alcohol Dependence, 113, pp. 86 - 87, http://www.sciencedirect.com/science/article/B6T63-5119FTB-4/2/1da704a3e06e8182fdff46a2d32dd183
2011
Koelsch KK; Boesecke C; Mcbride K; Gelgor L; Fahey P; Natarajan V; Baker D; Bloch M; Murray JM; Zaunders J; Emery S; Cooper DA; Kelleher AD, 2011, 'Impact of treatment with raltegravir during primary or chronic HIV infection on RNA decay characteristics and the HIV viral reservoir', AIDS, 25, pp. 2069 - 2078, http://dx.doi.org/10.1097/QAD.0b013e32834b9658
2011
Murray JM; Kelleher ; Cooper DA, 2011, 'Timing of the components of the HIV life cycle in productively infected CD4+ T cells in a population of HIV-infected individuals', Journal of Virology, 85, pp. 10798 - 10805, http://dx.doi.org/10.1128/JVI.05095-11
2011
Fernandez S; Tanaskovic S; Helbig K; Rajasuriar R; Kramski M; Murray JM; Beard M; Purcell DJ; Lewin S; Price P; French MA, 2011, 'CD4+ T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4+ T cells', Journal of Infectious Diseases, 204, pp. 1925 - 1927, http://dx.doi.org/10.1093/infidis/jir659
2011
Cysique LA; Bain MP; Brew BJ; Murray JM, 2011, 'The burden of HIV-associated neurocognitive impairment in Australia and its estimates for the future', Sexual Health, 8, pp. 541 - 550, http://search.informit.com.au/documentSummary;dn=535898181780976;res=IELHEA
2011
Murray JM; Prestage G; Grierson J; Middleton MG; Mcdonald A, 2011, 'Increasing HIV diagnoses in Australia among men who have sex with men correlated with the growing number not taking antiretroviral therapy', Sexual Health, 8, pp. 304 - 310, http://www.publish.csiro.au/paper/SH10114
2011
Vallely A; MacLaren DJ; Kaleva W; Millan J; Tommbe R; Marape W; Manineng C; Buchanan H; Amos A; Frank R; Kelly A; Kupul M; Aeno H; Trowalle E; John LN; Redman-Maclaren ML; Ryan C; Browne K; Tynan A; Hill PS; Gray RT; Murray J; Wilson DP; Law G; Siba P; McBride WJ; Farley T; Kaldor JM; National Policy Forum, Papua New Guinea , 2011, 'Male circumcision for HIV prevention in Papua New Guinea: a summary of research evidence and recommendations for public health following a national policy forum.', Papua and New Guinea medical journal, 54, pp. 91 - 108
2011
Lutgehetmann M; Volz T; Kopke A; Broja T; Tigges E; Lohse AW; Fuchs E; Murray JM; Petersen J; Dandri M, 2010, 'In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice', Hepatology, 52, pp. 16 - 24, http://dx.doi.org/10.1002/hep.23611
2010
Cysique LA; Murray JM; Dunbar M; Jeyakumar V; Brew BJ, 2010, 'A screening algorithm for HIV associated neurocognitive disorders', HIV Medicine, 11, pp. 642 - 649, http://dx.doi.org/10.1111/j.1468-1293.2010.00834.x
2010
Dunbar M; Murray JM; Cysique LA; Brew BJ; Jeyakumar V, 2010, 'Simultaneous classification and feature selection via convex quadratic programming with application to HIV-associated neurocognitive disorder assessment', European Journal of Operational Research, 206, pp. 470 - 478, http://www.sciencedirect.com/science/article/B6VCT-4YM7FH3-4/2/a3b9972e52fd64b1f7b5439ecdb15184
2010
Murray JM; Vallely A; Page A, 2010, 'When the presumption of innocence is not beneficial: periodic presumptive treatment for STIs and HIV in female sex workers', Sexually Transmitted Infections, 86, pp. 161 - 162, http://sti.bmj.com/content/86/3/161.short
2010
Londish GJ; Templeton DJ; Regan DG; Kaldor JM; Murray JM, 2010, 'Minimal impact of circumcision on HIV acquisition in men who have sex with men', Sexual Health, 7, pp. 463 - 470, http://dx.doi.org/10.1071/SH09080
2010
Vallely A; Page A; Dias S; Lupiwa T; Law G; Millan J; Wilson DP; Murray JM; Toole M; Kaldor JM, 2010, 'The Prevalence of Sexually Transmitted Infections in Papua New Guinea: A Systematic Review and Meta- Analysis', PLoS One, 5, pp. 1 - 10, http://dx.doi.org/10.1371/journal.pone.0015586
2010
Zeiler I; Langlands TA; Murray JM; Ritter A, 2010, 'Optimal targeting of Hepatitis C virus treatment among injecting drug users to those not enrolled in methadone maintenance programs', Drug and Alcohol Dependence, 110, pp. 228 - 233, http://www.sciencedirect.com/science/article/B6T63-4YYGPNG-1/2/fdcaccba640e0cc879679e1def9e1354
2010
Koelsch KK; Xu Y; Bailey M; McBride K; Seddiki N; Suzuki K; Murray J; Cooper DA; Kelleher AD; Zaunders J, 2010, 'Most HIV DNA in PBMC is present in non‐gut homing, resting memory CD4+ T cells with a ß7‐CD38‐CD127 high phenotype', Journal of the International AIDS Society, 13, http://dx.doi.org/10.1186/1758-2652-13-s3-o2
2010
Pett SL; Zaunders J; Bailey M; Murray JM; Macrae K; Emery S; Cooper DA; Kelleher AD, 2010, 'A novel Chemokine-Receptor-5 (CCR5) blocker, SCH532706, has differential effects on CCR5+CD4+ and CCR5+CD8+ T cell numbers in chronic HIV infection', AIDS Research and Human Retroviruses, 26, pp. 653 - 661, http://dx.doi.org/10.1089/aid.2009.0278
2010
Applegate TL; Birkett DJ; Mcintyre GJ; Jaramillo AB; Symonds G; Murray JM, 2010, 'In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy', Retrovirology, 7:83, pp. 1 - 14, http://www.retrovirology.com/content/7/1/83
2010
Murray JM; McDonald AM; Law MG, 2009, 'Rapidly ageing HIV epidemic among men who have sex with men in Australia', Sexual Health, 6, pp. 83 - 86, http://www.publish.csiro.au/paper/SH08063
2009
Byakwaga H; Murray JM; Petoumenos K; Kelleher AD; Law MG; Boyd MA; Emery S; Mallon PW; Cooper DA, 2009, 'Evolution of CD4+T cell count in HIV-1-infected adults receiving antiretroviral therapy with sustained long-term virological suppression', AIDS Research and Human Retroviruses, 25, pp. 569 - 576
2009
Murray JM; Fanning GC; Macpherson JL; Evans LA; Pond SM; Symonds GP, 2009, 'Mathematical modelling of the impact of haematopoietic stem cell-delivered gene theraphy for HIV', Journal of Gene Medicine, 11, pp. 1077 - 1086, http://dx.doi.org/10.1002/jgm.1401
2009
Mitsuyasu RT; Merigan T; Carr AD; Zack J; Winters M; Workman C; Bloch MT; Lalezari J; Becker S; Thornton L; Akil B; Khanlou H; Finlayson R; Mcfarlane R; Smith DE; Garsia R; Ma DD; Law MG; Murray JM; Von Kalle C; Ely JA; Patino S; Knop A; Wong P; Todd A; Haughton M; Fuery C; Marcpherson J; Symonds G; Evans L; Pond SM; Cooper DA; Cooper D; Han A, 2009, 'Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells', Nature Medicine, 15, pp. 285 - 292, http://dx.doi.org/10.1038/nm.1932
2009
Mcintyre GJ; Yu Y; Tran A; Jaramillo AB; Arndt AJ; Millington ML; Boyd MP; Elliott FA; Shen SW; Murray JM; Applegate TL, 2009, 'Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success', Virology Journal, 6, pp. 184, http://www.virologyj.com/content/6/1/184
2009
Dandri M; Petersen J; Murray JM, 2009, 'Reply: Hepatitis B virus clearance rate estimates', Hepatology, 49, pp. 1780 - 1781, http://dx.doi.org/10.1002/hep.22918
2009
Dandri M; Murray JM; Lutgehetmann M; Volz T; Lohse A; Petersen J, 2008, 'Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia', Hepatology, 48, pp. 1079 - 1086
2008
Srinivasan S; Holmyard D, 2008, 'Corneal stromal bed quality obtained with mechanical microkeratome and femtosecond laser.', Cornea, 27, pp. 746, http://dx.doi.org/10.1097/QAI.0b013e31815dbf7f
2008
Londish GJ; Murray JM, 2008, 'Significant reduction in HIV prevalence according to male circumcision intervention in sub-saharan Africa', International Journal of Epidemiology
2008
Byakwaga H; Murray JM; Petoumenos K; Boyd MA; Emery S; Mallon PW; Cooper DA, 2008, 'Evolution of CD4+ T-cell count in HIV-1 infected adults receiving antiretroviral therapy with sustained long-term virological suppression', Journal of the International AIDS Society, 11, http://dx.doi.org/10.1186/1758-2652-11-s1-p70
2008
Murray JM, 2008, 'HIV dynamics and integrase inhibitors', Antiviral Chemistry and Chemotherapy, 19, pp. 157 - 164
2008
Lewin S; Murray JM; Solomon A; Wightman F; Cameron P; Purcell DJ; Zaunders J; Grey PA; Bloch M; Smith DE; Cooper DA; Kelleher AD, 2008, 'Virologic determinants of success after structured treatment interruptions in antiretrovirals in acute HIV-1 infection', JAIDS: Journal of Acquired Immune Deficiency Syndromes, 47, pp. 140 - 147
2008
Murray JM; Emery S; Kelleher AD; Law MG; Chen J; Hazuda DJ; Nguyen BT; Teppler H; Cooper DA, 2007, 'Antiretroviral therapy with the integrase inhibitor raltegravir alters decay kinetics of HIV, significantly reducing the second phase', AIDS, 21, pp. 2315 - 2321
2007
Volz T; Lutgehetmann M; Wachtler P; Jacob A; Quaas A; Murray JM; Dandri M; Petersen J, 2007, 'Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients', Gastroenterology, 133, pp. 843 - 852
2007
Murray JM; Purcell RH; Wieland SF, 2006, 'The half-life of Hepatitis B virions', Hepatology, 44, pp. 1117 - 1121
2006
Murray JM; Perelson AS, 2005, 'Human immunodeficiency virus: Quasi-species and drug resistance', Multiscale Modeling and Simulation, 3, pp. 300 - 311
2005
Macpherson JL; Boyd MP; Arndt AJ; Todd AV; Ganning GC; Ely JA; Elliott F; Knop A; Raponi M; Murray JM; Gerlach W; Sun L; Penny R; Symonds GP; Carr AD; Cooper DA, 2005, 'Long-term survival and concomitant gene expression of ribozyme-transduced CD4+ T-lymphocytes in HIV-infected patients', Journal of Gene Medicine, 7, pp. 552 - 564
2005
Murray JM; Wieland SF; Purcell RH; Chisari FV, 2005, 'Dynamics of hepatitis B virus clearance in chimpanzees', Proceedings of the National Academy of Sciences of the United States of America, 102, pp. 17780 - 17785
2005
Murray JM; Law MG; Gao Z; Kaldor JM, 2003, 'The impact of behavioural changes on the prevalence of human immunodeficiency virus and hepatitis C among injecting drug users', International Journal of Epidemiology, 32, pp. 708 - 714, http://ije.oxfordjournals.org/content/32/5/708.abstract
2003
Murray JM; Coldman AJ, 2003, 'The effect of heterogeneity on optimal regimens in cancer chemotherapy', Mathematical Biosciences, 185, pp. 73 - 87
2003
Murray JM; Leigh Brown AJ; Frost SDW; Mathews WC; Dawson K; Hellmann NS; Daar ES; Richman DD; Little SJ, 2003, 'Changing Transmission Fitness of Drug-Resistant Human Immunodeficiency Virus against a Background of Evolving Antiretroviral Therapy [1] (multiple letters)', Journal of Infectious Diseases, 188, pp. 1258 - 1259, http://dx.doi.org/10.1086/378679
2003
Murray JM; Kaufmann GR; Hodgkin PD; Lewin SR; Kelleher AD; Davenport MP; Zaunders JJ, 2003, 'Naive T cells maintained by thymic output in early ages but by proliferation without phenotypic change after age twenty', Immunology and Cell Biology, 81, pp. 487 - 495
2003
Markowitz M; Jin XC; Hurley A; Simon V; Ramratnam B; Louie M; Deschenes GR; Ramanathan JM; Barsoum S; Vanderhoeven J; He T; Chung C; Murray JM; Perelson AS; Zhang L; Ho D, 2002, 'Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination', Journal of Infectious Diseases, 186, pp. 634 - 643
2002
Whalley SA; Murray JM; Brown D; Webster GJ; Emery VC; Dusheiko G; Perelson AS, 2001, 'Kinetics of acute hepatitis B virus infection in humans', Journal of Experimental Medicine, 193, pp. 847 - 853
2001
Kaufmann GR; Zaunders J; Murray JM; Kelleher AD; Lewin S; Solomon A; Smith DE; Cooper DA, 2001, 'Relative significance of different pathways of immune reconstitution in HIV type 1 infection as estimated by mathematical modelling.', AIDS Research and Human Retroviruses, 17, pp. 147 - 159
2001
Coldman AJ; Murray JM, 2000, 'Optimal control for a stochastic model of cancer chemotherapy', Mathematical Biosciences, 168, pp. 187 - 200
2000
Murray JM; Kaufmann GR; Kelleher AD; Cooper DA, 1998, 'A model of primary HIV-1 infection', Mathematical Biosciences, 154, pp. 57 - 85
1998
Murray JM, 1997, 'The optimal scheduling of two drugs with simple resistance for a problem in cancer chemotherapy', IMA Journal of Mathematics Applied in Medicine and Biology, 14, pp. 283 - 303
1997
Murray JM, 1995, 'An example of the effects of drug resistance on the optimal schedule for a single drug in cancer chemotherapy.', IMA Journal of Mathematics Applied in Medicine and Biology, 12, pp. 55 - 69
1995
Murray JM, 1994, 'Optimal drug regimens in cancer chemotherapy for single drugs that block progression through the cell cycle', Mathematical Biosciences, 123, pp. 183 - 213, http://dx.doi.org/10.1016/0025-5564(94)90011-6
1994
Murray JM, 1990, 'Optimal control for a cancer chemotheraphy problem with general growth and loss functions', Mathematical Biosciences, 98, pp. 273 - 287, http://dx.doi.org/10.1016/0025-5564(90)90129-M
1990
Murray JM, 1990, 'Some optimal control problems in cancer chemotherapy with a toxicity limit', Mathematical Biosciences, 100, pp. 49 - 67, http://dx.doi.org/10.1016/0025-5564(90)90047-3
1990
MURRAY JM, 1989, 'OPTIMAL-CONTROL PROBLEMS WITH ELASTIC COLLISIONS', JOURNAL OF THE AUSTRALIAN MATHEMATICAL SOCIETY SERIES B-APPLIED MATHEMATICS, 30, pp. 470 - 482, http://dx.doi.org/10.1017/S0334270000006408
1989
Murray JM, 1986, 'EXISTENCE THEOREMS FOR OPTIMAL CONTROL AND CALCULUS OF VARIATIONS PROBLEMS WHERE THE STATES CAN JUMP.', SIAM Journal on Control and Optimization, 24, pp. 412 - 438, http://dx.doi.org/10.1137/0324024
1986
MURRAY JM, 1985, 'SIMPLE NONLINEAR DUAL CONTROL-PROBLEMS', JOURNAL OF THE AUSTRALIAN MATHEMATICAL SOCIETY SERIES B-APPLIED MATHEMATICS, 27, pp. 131 - 144, http://dx.doi.org/10.1017/S0334270000004835
1985
Murray JM, 1985, 'Some existence and regularity results for dual linear control problems', Journal of Mathematical Analysis and Applications, 112, pp. 190 - 209, http://dx.doi.org/10.1016/0022-247X(85)90285-9
1985
Murray JM; Teo KL, 1978, 'On a computational algorithm for a class of optimal control problems involving discrete time delayed arguments', Journal of the Australian Mathematical Society, Series B, 20, pp. 315 - 343
1978
Preprints
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Kyaw W; Chai RC; Khoo WH; Goldstein LD; Croucher PI; Murray JM; Phan TG, 2023, ENTRAIN: integrating trajectory inference and gene regulatory networks with spatial data to co-localize the receptor-ligand interactions that specify cell fate, , http://dx.doi.org/10.1101/2023.07.09.548284
2023
Wade S; Weber MF; Sarich P; Vaneckova P; Behar-Harpaz S; Ngo PJ; Cressman S; Gartner CE; Murray JM; Blakely TA; Banks E; Tammemagi MC; Canfell K; Caruana M, 2022, Bayesian calibration of simulation models: A tutorial and an Australian smoking behaviour model, , http://arxiv.org/abs/2202.02923v2
2022
Hall M; Simms K; Murray J; Keane A; Nguyen TND; Caruana M; Liu G; Kelly H; Eckert L; Santesso N; DeSanjose S; Swai E; Rangaraj A; Owiredu MN; Gauvreau C; Demke O; Basu P; Arbyn M; Dalal S; Broutet N; Canfell K, 2022, Evaluation of the benefits and harms of alternative strategies for cervical screening and treatment in women living with HIV: modelling to support WHO 2021 cervical screening and treatment guidelines to prevent cervical cancer, , http://dx.doi.org/10.21203/rs.3.rs-2403727/v1
2022
Stancevic O; Angstmann C; Murray JM; Henry BI, 2012, Turing patterns from dynamics of early HIV infection over a two-dimensional surface, , http://dx.doi.org/10.48550/arxiv.1209.2772
2012
Conference Papers
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Ledger S; Howe A; Murray J; Symonds G, 2014, 'Lentiviral Vector Mediated Gene Therapies Provide Stable Protection Against HIV Infection: The Use of Short-Hairpin RNA to CCR5 and Membrane Anchored C Peptide Entry Inhibitors', in MOLECULAR THERAPY, NATURE PUBLISHING GROUP, DC, Washington, pp. S271 - S271, presented at 17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), DC, Washington, 21 May 2014 - 24 May 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000337231300693&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Savkovic B; Ledger S; Symonds GP; Murray JM, 2013, 'Mathematical modelling in anti-HIV gene therapy: estimating clinically relevant parameters and predicting likely clinical outcomes', in Proceedings of the 49th ANZIAM Conference, ANZIAM, Newcastle Australia 2013, pp. 87 - 88, presented at Australian and New Zealand Industrial and Applied Mathematics Conference (ANZIAM 2013), Newcastle, Australia, 03 February 2013 - 07 February 2013, http://anziam2013.newcastle.edu.au/anziam2013proceedings.pdf
2013
Moenne-Loccoz R; Velay A; Murray J; Habersetzer F; Doffoel M; Fafi-Kremer S; Zeisel MB; Fofana I; Gut J-P; Baumert TF; Stoll-Keller F; Schvoerer E, 2011, 'HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN SIGNATURES AND RESISTANCE TO ANTIVIRAL TREATMENT', in JOURNAL OF HEPATOLOGY, ELSEVIER, GERMANY, Berlin, pp. S484 - S484, presented at 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), GERMANY, Berlin, 30 March 2011 - 03 April 2011, http://dx.doi.org/10.1016/S0168-8278(11)61228-2
2011
Koelsch KK; Xu Y; Bailey M; McBride K; Seddiki N; Suzuki K; Murray J; Cooper DA; Kelleher AD; Zaunders J, 2010, 'Most HIV DNA in PBMC is present in non-gut-homing, resting central memory CD4 T-cells', in ANTIVIRAL THERAPY, INT MEDICAL PRESS LTD, Dubrovnik, CROATIA, pp. A44 - A44, presented at International HIV and Hepatitis Virus Drug Resistance and Curative Strategies Workshop, Dubrovnik, CROATIA, 08 June 2010 - 12 June 2010
2010
Dandri M; Murray JE; Luetgehetmann M; Volz T; Lohse A; Petersen JA, 2008, 'Virion half-life in chronic hepatitis B infection is strongly correlated with viral load', in Journal of Hepatology, Elsevier Science BV, Amsterdam, Netherlands, pp. S30 - S31, presented at Journal of Hepatology
2008
Volz T; Lutgehetmann M; Quaas A; Murray JW; Dandri M; Petersen J, 2007, 'Reduced HBV replication in HBeAg-negative patients is due to lower covalently closed circular DNA content and impaired virion productivity', in HEPATOLOGY, JOHN WILEY & SONS INC, MA, Boston, pp. 638A - 638A, presented at 58th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, MA, Boston, 02 November 2007 - 06 November 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000249910401165&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Conference Abstracts
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Danta M; Zaunders J; Bailey MR; Marks K; Seddiki N; Emery S; Murray JM; Cooper DA; Koelsch K; Kelleher AD, 2012, 'Primary HIV-1 infection (PHI) is associated with reduced CD4 cell counts in terminal ileum biopsies, but not other gut biopsy sites', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, Vol. 27, pp. 19 - 19, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308642600039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Book Chapters
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Ledger S; Savkovic B; Millington ML; Impey H; Boyd M; Murray JM; Symonds G, 2011, 'Cell-delivered gene theraphy for HIV', in Tang Y (ed.), Recent Translational Research in HIV/AIDS, InTech, Croatia, pp. 405 - 430, http://dx.doi.org/10.5772/22658
2011

AREA OF EXPERTISE
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Mathematical biology

Organisational units
lensChief Investigators